Olympique Lyon and France defender Anthony Reveillere will be out for the rest of the season with a knee injury.
"He tore a cruciate ligament in his left knee and will miss the rest of the season," Lyon coach Claude Puel said before adding the right back would probably need surgery.
Reveillere, who has five caps, picked up the injury 11 minutes into Saturday's 1-0 defeat at Paris St Germain in Ligue 1.
Lyon, who travel to Fiorentina in the Champions League on Tuesday, are already without France defender Francois Clerc until January because of a knee injury.
Lamine Gassama, 19, is expected to deputise for the Ligue 1 champions in Florence.