The Leader has superhuman mental acumen, as a result of his exposure to an explosion of gamma-irradiated waste. He possesses enhanced intuition, pattern solving, information storage and retrieval, and logical and philosophical structuring. His ability to predict probable outcomes of tactical and strategic scenarios is so advanced that it borders on clairvoyance. The Leader has a perfect memory with the ability to recall every moment since the accident that gave him his powers. In addition to his superhuman intelligence, the Leader has limited but potent telekinetic and telepathic powers. He is able to mentally control non-gamma-mutated individuals upon touching them, and is capable of battling the Hulk with his telekinetic powers.
The Leader possesses knowledge of genetics, physics, and robotics, and has designed a large number of sophisticated weapons, vehicles, computers, androids, and synthetic humanoids. He is particularly adept at genetic engineering and manipulating radiation for various nefarious purposes.